Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2
Clonality
Polyclonal
稀釋度
WB 1:2000
預(yù)測(cè)分子量
103kDa
宿主
Rabbit
同種型
IgG
細(xì)胞定位
Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm (By similari
ty).
特異性
This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptid
e between 878-910 amino acids from DANRE srrt.
背景介紹
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cel
l proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA process
ing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its a
ctivity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 pro
moter and positively regulating its transcription (By similarity).
All lanes : Anti-srrt Antibody (C-Term) at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: Jurkat whole cell lysates Lane 3: NIH/3T3 whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate